![]() ![]() Right eye floater that progressed gradually from the periphery toward the centerĪcute Macular Neuroretinopathy following Coronavirus Disease 2019 Vaccination.Īcute Macular Neuroretinopathy After COVID-19 Vaccine. A review of the incidence of such conditions is timely and would be beneficial to ophthalmologists and general physicians alike, in identifying patients who may be at a higher risk of ocular adverse events so that protocols for close monitoring of patients at risk can be designed and implemented.īilateral superior ophthalmic vein thrombosis, ischaemic stroke, and immune thrombocytopenia after ChAdOx1 nCoV-19 vaccination.Ī case report of bilateral superior ophthalmic vein thrombosis post-vaccinationĬonjunctival congestion, retroorbital pain, diplopiaĪcute macular neuroretinopathy following COVID-19 vaccination.Ī case report of acute macular neuroretinopathy (AMN) post-vaccinationīilateral Acute Macular Neuroretinopathy After Vaccination Against SARS-CoV-2Ī case report of Bilateral Acute Macular Neuroretinopathy post-vaccinationīell’s palsy following COVID-19 vaccinationĪ case report of Bell’s Palsy post-vaccinationĪcute corneal endothelial graft rejection following COVID-19 vaccinationĪ case report of DMEK rejection post-vaccinationĪcute Uveitis following COVID-19 VaccinationĪ case report of juvenile idiopathic arthritis-associated anterior uveitis post-vaccinationĪcute-onset central serous retinopathy after immunization with COVID-19 mRNA vaccine.Ī case report of acute-onset central serous retinopathy (CSR) post-vaccinationīilateral Multifocal Choroiditis following COVID-19 VaccinationĪ case report of bilateral multifocal choroiditis post-vaccination ![]() This review provides a comprehensive overview of COVID-19 vaccine-induced ocular adverse effects. While their respective trial reports on vaccine safety have shown that ocular adverse effects are rare, the possible manifestations are still a cause for concern, given the scale of the current vaccination campaign against COVID-19. These include mRNA vaccines (BNT162b2, Pfizer-BioNTech 14 mRNA-1273, Moderna 15), protein subunit vaccines (NVX-CoV2373, Novavax 16), vector vaccines (Ad26.COV2, Janssen Johnson & Johnson 17 ChAdOx1 nCoV-19/ AZD1222, Oxford-AstraZeneca 18), and whole virus vaccines (PiCoVacc, Sinovac 19 BBIBP-CorV, Sinopharm 20). There are currently four types of COVID-19 vaccines. Some of the reported ocular manifestations of COVID-19 infection include conjunctivitis, episcleritis, uveitis, vascular changes in the retina and cotton wool spots, optic neuritis, ocular motility deficits from cranial nerve palsies, and transient accommodation deficits. 1–7 The surge in the literature on COVID-19 and rapid development of vaccination regimens has produced reports on the ocular manifestations of COVID-19, as well as ocular adverse effects of COVID-19 vaccinations. For example, vaccinations against influenza, yellow fever, hepatitis B, and Neisseria meningitidis have been associated with uveitis, acute idiopathic maculopathy, acute macular neuroretinopathy (AMN), Vogt-Koyanagi-Harada disease (VKH), and multiple evanescent white dot syndrome (MEWDS). Historically, vaccines have been known to be associated with ocular phenomena. ![]()
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